CHEK2
Description
The CHEK2 gene plays a crucial role in cell cycle regulation, acting as a DNA damage checkpoint. It encodes a protein kinase that responds to DNA damage, triggering cell cycle arrest, DNA repair, or apoptosis. This ensures genomic stability, preventing mutations and cancer development. However, mutations in CHEK2 can disrupt its function, leading to increased cancer susceptibility and other diseases.
Associated Diseases
Did you know?
CHEK2 mutations are more common in certain populations, suggesting genetic predisposition to cancer.
