CHD9
Description
The CHD9 (chromodomain helicase DNA binding protein 9) is a protein-coding gene located on chromosome 16.
Chromodomain-helicase-DNA-binding protein 9 is an enzyme encoded by the CHD9 gene in humans. It is involved in bone development and differentiation.
CHD9 acts as a transcriptional coactivator for PPARA and possibly other nuclear receptors. It is proposed to be an ATP-dependent chromatin remodeling protein. It exhibits DNA-dependent ATPase activity and binds to A/T-rich DNA. CHD9 associates with A/T-rich regulatory regions in promoters of genes involved in the differentiation of progenitor cells during bone formation (osteogenesis).
CHD9 is also known as AD013, CHD-9, CReMM, KISH2, PRIC320.
