CETN1
Description
The CETN1 (centrin 1) is a protein-coding gene located on chromosome 18.
Centrin-1 is a protein encoded by the CETN1 gene in humans. It belongs to the centrin family of proteins. Centrin-1 plays vital roles in determining centrosome position and segregation, as well as in microtubule severing. This protein is found in the centrosome of interphase cells and relocates to the spindle poles during mitosis, reflecting the dynamic nature of the centrosome during the cell cycle.
CETN1 is also known as CEN1, CETN.
Associated Diseases
- male infertility with teratozoospermia due to single gene mutation
- partial chromosome Y deletion
- spermatogenic failure 65
- spermatogenic failure, X-linked, 3
- spermatogenic failure 10
- spermatogenic failure 72
- spermatogenic failure 11
- spermatogenic failure 40
- congenital bilateral absence of vas deferens
- spermatogenic failure 18
- spermatogenic failure 46
- spermatogenic failure 27
- spermatogenic failure 47
- spermatogenic failure 39
- spermatogenic failure 49
- spermatogenic failure 19
- spermatogenic failure 43
- spermatogenic failure 45
- deafness-infertility syndrome
- spermatogenic failure 41
- spermatogenic failure 42
