CERS4

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Description

The CERS4 (ceramide synthase 4) is a protein-coding gene located on chromosome 19.

Ceramide synthase 4 (CerS4) catalyzes the formation of ceramide, a vital lipid, by combining sphinganine with long-chain fatty acids (C18:0-C22:0) derived from acyl-CoA molecules. This process is crucial for maintaining cellular functions and responses to various stimuli.

CERS4 is also known as LASS4, Trh1.

Associated Diseases

• refractive error
• hypotrichosis simplex
• uncombable hair syndrome
• Clouston syndrome
• Olmsted syndrome 1
• pili torti