CENPK
Description
The CENPK (centromere protein K) is a protein-coding gene located on chromosome 5.
Centromere protein K is a protein that in humans is encoded by the CENPK gene. CENPK has been shown to interact with SOX6.
CENPK is part of the CENPA-CAD complex, which is recruited to centromeres and plays a crucial role in assembling kinetochore proteins, regulating mitotic progression, and ensuring accurate chromosome segregation. It may also facilitate the integration of newly synthesized CENPA into centromeres by interacting with the CENPA-NAC complex. Additionally, CENPK collaborates with KNL1 to recruit the NDC80 complex to the outer kinetochore.
CENPK is also known as AF5alpha, CENP-K, FKSG14, P33, Solt.
