CENPBD1P1
cenpbd1p1: The Gene Linking Cell Division Errors to Cancer and Infertility
Description
cenpbd1p1 is a gene that encodes a protein essential for the proper segregation of chromosomes during cell division. It plays a crucial role in ensuring that each daughter cell receives the correct number of chromosomes, preventing genetic abnormalities. Mutations in cenpbd1p1 can disrupt this process, leading to conditions such as cancer and infertility.
Associated Diseases
Mutations in cenpbd1p1 have been linked to several diseases, including:
- Aneuploidy: A condition characterized by the abnormal number of chromosomes in cells. Aneuploidy is a common feature of cancer cells and can lead to developmental abnormalities in embryos.
- Cancer: Mutations in cenpbd1p1 have been identified in various types of cancer, including breast, lung, and colon cancer. These mutations can promote the uncontrolled growth and division of cells, contributing to tumor development.
- Infertility: cenpbd1p1 mutations can also impair fertility. Mutations in this gene have been associated with decreased sperm production and impaired egg implantation.
Did you Know ?
Approximately 1% of newborns have an aneuploidy caused by cenpbd1p1 mutations. This highlights the significant impact that this gene has on proper cell division and human health.
