CELA2B


Description

The CELA2B (chymotrypsin like elastase 2B) is a protein-coding gene located on chromosome 1.

Chymotrypsin-like elastase family member 2B is an enzyme that in humans is encoded by the CELA2B gene. Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Like most of the human elastases, elastase 2B is secreted from the pancreas as a zymogen. In other species, elastase 2B has been shown to preferentially cleave proteins after leucine, methionine, and phenylalanine residues.

CELA2B is also known as ELA2B.

Associated Diseases



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