CECR2
Description
The CECR2 gene, also known as the ‘chromatin licensing and DNA replication factor 2‘ gene, plays a crucial role in DNA replication and repair. It encodes a protein involved in the licensing of DNA replication origins, ensuring that each DNA strand is copied only once per cell cycle. This intricate process is essential for maintaining genomic stability and preventing the accumulation of mutations that can lead to cancer. Mutations in CECR2 can disrupt this precise regulation, increasing the risk of developing various cancers, including leukemia, lymphoma, and breast cancer.
Associated Diseases
Did you know?
Mutations in CECR2 are more prevalent in individuals with Fanconi anemia, a rare genetic disorder characterized by bone marrow failure, developmental abnormalities, and an increased risk of cancer.
