CDNF


Description

The CDNF (cerebral dopamine neurotrophic factor) is a protein-coding gene located on chromosome 10.

CDNF is a gene that encodes a protein involved in the growth and survival of dopamine neurons in the brain. It may also be known as ARMET-like protein 1 or Conserved dopamine neurotrophic factor.

CDNF is a trophic factor that promotes the survival and function of dopamine neurons. It protects these neurons from damage caused by 6-hydroxydopamine (6-OHDA), a toxin that is commonly used to model Parkinson's disease. When administered after 6-OHDA-induced damage, CDNF can restore dopamine function and prevent further degeneration of these neurons in the substantia nigra.

CDNF is also known as ARMETL1.

Associated Diseases



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