CDK4
Description
The CDK4 gene encodes a protein kinase known as cyclin-dependent kinase 4, a crucial component of the cell cycle machinery. CDK4, in conjunction with its cyclin D partner, plays a vital role in regulating the G1-to-S phase transition, ensuring proper DNA replication and cell division. This intricate process involves phosphorylation of specific target proteins, influencing cell growth and proliferation.
Associated Diseases
Did you know?
Mutations in the CDK4 gene can lead to the development of cancer, highlighting its crucial role in maintaining normal cell growth and division.