CDC20B

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Description

The CDC20B (cell division cycle 20B) is a protein-coding gene located on chromosome 5.

CDC20B is a protein that plays a key role in the formation of cilia, specifically in multiciliated cells (MCCs). It acts as a regulator, facilitating the separation of centrioles (the structures that form cilia) from deuterosomes (organelles involved in cilia formation). This separation is essential for the subsequent development of cilia in MCCs.

CDC20B is also known as G6VTS76519.

Associated Diseases

• primary familial polycythemia due to EPO receptor mutation
• hemolytic anemia due to diphosphoglycerate mutase deficiency
• erythrocytosis, familial, 3
• erythrocytosis, familial, 6
• erythrocytosis, familial, 4
• hemoglobin E-beta-thalassemia syndrome
• dehydrated hereditary stomatocytosis
• hemolytic anemia due to erythrocyte adenosine deaminase overproduction
• alpha thalassemia-intellectual disability syndrome type 1
• gluthathione peroxidase deficiency
• elliptocytosis 2
• X-linked sideroblastic anemia 1
• Rh deficiency syndrome
• cryohydrocytosis
• IRIDA syndrome
• delta-beta-thalassemia
• hypertriglyceridemia 2