CD300LB
Description
The CD300LB (CD300 molecule like family member b) is a protein-coding gene located on chromosome 17.
CD300LB is a protein encoded by the CD300LB gene in humans. It belongs to the nonclassical activating receptors of the immunoglobulin (Ig) superfamily and is expressed on myeloid cells. CD300LB plays a role in the immune system as an activating receptor.
CD300LB acts as an activating immune receptor. It achieves this through two mechanisms: by interacting with the ITAM-bearing adapter TYROBP and independently by recruiting GRB2.
CD300LB is also known as CD300b, CLM-7, CLM7, CMRF35-A2, IREM-3, IREM3, TREM-5, TREM5.