CCDC85B
Description
The CCDC85B (coiled-coil domain containing 85B) is a protein-coding gene located on chromosome 11.
CCDC85B, or Coiled-coil domain-containing protein 85B, is a human protein encoded by the CCDC85B gene. It interacts with the hepatitis delta virus antigen (HDAg) and can affect HDV replication in vitro. CCDC85B interacts with several other proteins, including C19orf25, KIAA1267, Keratin 17, and Protein kinase N1.
CCDC85B acts as a transcriptional repressor, potentially inhibiting CTNNB1 activity in a TP53-dependent manner, thus influencing cell growth. It may play a role in adipocyte differentiation by negatively regulating mitotic clonal expansion. Its interaction with beta-catenin family proteins suggests involvement in cell-cell adhesion and epithelium development.
CCDC85B is also known as DIPA.
