CCDC3
Description
The CCDC3 (coiled-coil domain containing 3) is a protein-coding gene located on chromosome 10.
CCDC3, or Coiled-coil domain-containing protein 3, is a protein encoded by the CCDC3 gene in humans. It is involved in various cellular processes, including inflammation and lipid metabolism.
CCDC3 plays a role in regulating inflammation and lipid metabolism. It inhibits the inflammatory response triggered by TNF-alpha in endothelial cells by suppressing NF-kappaB activation. Additionally, CCDC3 promotes lipid accumulation in adipose cells, suggesting a role in fat storage.
CCDC3 is also known as -.
Associated Diseases
- CIDEC-related familial partial lipodystrophy
- AKT2-related familial partial lipodystrophy
- familial partial lipodystrophy, Kobberling type
- LIPE-related familial partial lipodystrophy