LZTS1

The LZTS1 gene builds a protein called leucine zipper tumor suppressor 1. This protein acts like a security guard in the cell, helping to regulate cell growth and division. It does this by interacting with other proteins and DNA to ensure proper cell cycle progression.

Associated Diseases

Lung cancer (NSCLC), Breast cancer, Prostate cancer, Esophageal squamous cell carcinoma, Colorectal cancer (potential association)

Did you know

Mutations in LZTS1 have been linked to an increased risk of various cancers, but the exact mechanisms are still under investigation. Interestingly, some studies suggest that even slight variations (not necessarily full mutations) in the LZTS1 gene might influence cancer susceptibility