CAMP
Description
The CAMP (cathelicidin antimicrobial peptide) is a protein-coding gene located on chromosome 3.
CAMP, cAMP or camP may stand for:
CAMP (Cathelicidin antimicrobial peptide) is a crucial component of the innate immune system, playing a role in antimicrobial defense. It binds to bacterial lipopolysaccharides (LPS), a key component of the outer membrane of Gram-negative bacteria. This binding triggers a response that enhances the release of CXCL2, a chemokine that attracts neutrophils to the site of infection. Additionally, CAMP is processed into shorter peptides that provide topical antimicrobial protection in sweat on the skin. Notably, even the unprocessed precursor form of CAMP effectively inhibits the growth of Gram-negative bacteria like E. coli and E. aerogenes.
CAMP is also known as CAP-18, CAP18, CRAMP, FALL-39, FALL39, HSD26, LL37.
Associated Diseases
- endometrial cancer
- immunodeficiency 28
- recurrent Neisseria infections due to factor D deficiency
- varicella, severe recurrent
- candidiasis, familial, 4
- type II complement component 8 deficiency
- systemic lupus erythematosus
- breast cancer
- mannose-binding lectin deficiency
- X-linked severe congenital neutropenia
