CALCA
Description
The calca gene, encodes for the precursor protein of calcitonin, a hormone crucial for calcium regulation in the body. This gene also produces other peptide hormones, such as calcitonin gene-related peptide (CGRP) and adrenomedullin, which have diverse roles in various physiological processes. Calca plays a vital role in maintaining calcium homeostasis by influencing bone metabolism, renal calcium reabsorption, and intestinal calcium absorption. It also contributes to regulating blood pressure, promoting vasodilation, and mediating pain sensation.
Associated Diseases
- Hypercalcemia
- Hypocalcemia
- Osteoporosis
- Paget‘s disease of bone
- Migraine
- Cluster headaches
- Familial Mediterranean fever
- Amyloidosis
Did you know?
Calcitonin gene-related peptide (CGRP) is a potent vasodilator and plays a crucial role in migraine headaches. Blocking CGRP receptors has become a promising therapeutic target for migraine prevention.
