C6orf89
c6orf89: A Promising Gene for Understanding Complex Diseases
Description
c6orf89 is a relatively unstudied gene located on chromosome 6. It encodes a protein of unknown function. However, recent research has identified its potential role in several complex diseases, including cancer, neurodegenerative disorders, and autoimmune conditions.
Associated Diseases
Cancer:
- Breast cancer: c6orf89 overexpression has been associated with increased tumor size, lymph node involvement, and worse prognosis.
- Ovarian cancer: High c6orf89 levels are linked to advanced disease stage and reduced survival.
- Lung cancer: c6orf89 may promote tumor growth and metastasis.
Neurodegenerative disorders:
- Alzheimer‘s disease: Alterations in c6orf89 expression may contribute to cognitive decline and memory loss.
- Parkinson‘s disease: c6orf89 mutations may increase susceptibility to the disorder.
- Multiple sclerosis: c6orf89 has been implicated in the inflammatory processes associated with MS.
Autoimmune conditions:
- Rheumatoid arthritis: c6orf89 variants may influence disease severity and response to treatment.
- Systemic lupus erythematosus: c6orf89 may play a role in the immune dysregulation characteristic of SLE.
- Type 1 diabetes: c6orf89 is a potential susceptibility gene for the disease.
Did you Know ?
Research suggests that a common genetic variant in c6orf89 is associated with an increased risk of breast cancer by approximately 15%.
