C18orf56
c18orf56 Gene: An Emerging Player in Disease and Research
Description
The c18orf56 gene, also known as chromosome 18 open reading frame 56, encodes a protein called coiled-coil domain-containing protein 56. This protein is involved in various cellular processes, including protein degradation, cell cycle regulation, and immune response.
Associated Diseases
Mutations in the c18orf56 gene have been linked to the following diseases:
- Myeloid malignancies: Acute myeloid leukemia, myelodysplastic syndromes, and chronic myelomonocytic leukemia
- Solid tumors: Lung cancer, breast cancer, and colon cancer
- Immune disorders: Rheumatoid arthritis and inflammatory bowel disease
- Neurological disorders: Amyotrophic lateral sclerosis and Alzheimer's disease
Did you Know ?
Approximately 5-10% of myeloid leukemia patients carry mutations in the c18orf56 gene, making it one of the most commonly mutated genes in this type of cancer.
