C17orf112
c17orf112: An Intriguing Gene with Diverse Roles and Potential Implications
Description
c17orf112, also known as chromosome 17 open reading frame 112, is a gene located on chromosome 17 in humans. It encodes a protein with a predicted molecular weight of approximately 112 kilodaltons. The c17orf112 gene is highly conserved across species, suggesting its functional importance.
Function
The exact function of c17orf112 is still not fully understood. However, studies have shed light on its involvement in various cellular processes, including:
- Cell cycle regulation: c17orf112 has been found to play a role in regulating cell growth and division.
- DNA repair: Research suggests that c17orf112 may be involved in the repair of damaged DNA.
- Immune response: The gene has been linked to immune system function, particularly the production of certain cytokines.
Associated Diseases
Mutations or alterations in the c17orf112 gene have been associated with several diseases and disorders, including:
- Lung cancer: Studies have found that decreased expression of c17orf112 is associated with increased risk and poor prognosis in lung cancer patients.
- Breast cancer: c17orf112 has been implicated in the development and progression of breast cancer.
- Ovarian cancer: Mutations in c17orf112 have been identified in some cases of ovarian cancer.
- Neurodevelopmental disorders: Certain genetic variations in c17orf112 have been linked to neurodevelopmental disorders such as autism spectrum disorder.
Did you Know ?
According to a recent study, individuals with a certain genetic variant in the c17orf112 gene have a 20% higher risk of developing lung cancer compared to those without the variant.
