C15orf43
c15orf43: A Gene with Widespread Implications
Description
c15orf43 (chromosome 15 open reading frame 43) is a gene located on chromosome 15 in humans. It encodes a protein of unknown function, but studies have linked it to a variety of biological processes and diseases.
Associated Diseases
c15orf43 has been associated with several diseases and disorders, including:
- Obesity: Individuals with certain variations in the c15orf43 gene have an increased risk of obesity and weight gain.
- Type 2 Diabetes: c15orf43 variants have also been linked to an increased risk of developing type 2 diabetes.
- Polycystic Ovary Syndrome (PCOS): Women with PCOS have higher levels of c15orf43 protein, suggesting a possible role in the development of this condition.
- Neurodevelopmental Disorders: Some studies have investigated the potential link between c15orf43 and neurodevelopmental disorders such as autism spectrum disorder (ASD) and ADHD.
Did you Know ?
A large-scale genome-wide association study identified c15orf43 as one of the most significantly associated genes with obesity, with certain variants increasing the likelihood of obesity by up to 50%.
