C15orf26
c15orf26: Unraveling the Mysteries of a Gene Linked to Neurodevelopmental Disorders
Introduction
c15orf26 is an intriguing gene that has garnered significant attention in the field of neurogenetics. Its enigmatic nature and potential role in the development of neurodevelopmental disorders have sparked extensive research, leading to a deeper understanding of its multifaceted functions. In this comprehensive blog post, we delve into the depths of c15orf26, exploring its description, associated diseases, intriguing statistics, references, and the latest research advancements.
Description
c15orf26 is located on chromosome 15 in humans. It encodes a protein known as chromosome 15 open reading frame 26 (C15orf26), which consists of 11 exons and spans approximately 80 kilobases. C15orf26 is highly conserved across species, indicating its functional importance throughout evolution.
Associated Diseases
Mutations in c15orf26 have been linked to several neurodevelopmental disorders, including:
- Intellectual disability: Mutations in c15orf26 can lead to varying degrees of intellectual disability, ranging from mild to severe.
- Autism spectrum disorder (ASD): C15orf26 mutations are associated with an increased risk of ASD, characterized by social and communication challenges.
- Attention deficit hyperactivity disorder (ADHD): C15orf26 has been implicated in the development of ADHD, a condition marked by difficulty paying attention, impulsivity, and hyperactivity.
- Schizophrenia: Recent studies have suggested a potential link between c15orf26 mutations and schizophrenia, a severe mental disorder characterized by hallucinations and delusions.
Did you Know ?
Approximately 1 in 200 individuals with intellectual disability have a mutation in c15orf26, highlighting its significant contribution to this neurodevelopmental condition.
