C10orf32
c10orf32: A Genomic Enigma Linked to Neurological Disorders
Description
c10orf32 is a gene located on chromosome 10 in the human genome. It encodes a protein of unknown function, despite its involvement in several critical cellular processes. c10orf32 is expressed in various tissues, including the brain, heart, and liver.
Associated Diseases
Mutations in c10orf32 have been linked to various neurological disorders, including:
- Amyotrophic lateral sclerosis (ALS): A fatal neurodegenerative disorder affecting the motor neurons of the spinal cord and brain.
- Frontotemporal dementia (FTD): A group of neurodegenerative disorders characterized by changes in personality, behavior, and language.
- Alzheimer's disease: The most common form of dementia, affecting memory, cognition, and behavior.
- Parkinson's disease: A neurodegenerative disorder that affects movement, coordination, and speech.
Did you Know ?
Research suggests that mutations in c10orf32 are present in approximately 10% of familial ALS cases and 5% of sporadic ALS cases.
