C10orf113
c10orf113: A Gene Linked to Neurological Disorders
Introduction
c10orf113 is a gene located on the human chromosome 10. It is involved in various neurobiological processes and has been associated with several neurological disorders. This blog post will delve into the description, associated diseases, an interesting statistic, references, and additional information on the latest research related to c10orf113.
Description
The c10orf113 gene encodes a protein known as chromosome 10 open reading frame 113 (C10orf113). The C10orf113 protein is a transmembrane protein with roles in neurodevelopment and synaptic function. It is highly expressed in the brain, particularly in the hippocampus and cerebellum.
Associated Diseases
Mutations in the c10orf113 gene have been linked to several neurological disorders, including:
- Schizophrenia: c10orf113 has been identified as a risk gene for schizophrenia, a mental disorder characterized by hallucinations, delusions, and cognitive impairments.
- Autism Spectrum Disorder (ASD): Mutations in c10orf113 have also been associated with ASD, a developmental disorder characterized by social communication difficulties and repetitive behaviors.
- Epilepsy: c10orf113 mutations have been linked to certain types of epilepsy, a neurological disorder characterized by recurrent seizures.
Did you Know ?
A large-scale genetic study found that approximately 1% of individuals with schizophrenia have mutations in the c10orf113 gene. This suggests that c10orf113 is a significant genetic risk factor for schizophrenia.
