Pharmacogenomics and the Path to Personalized Medicine

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Path to Personalized Medicine:

If you see in today‘s modern world, mankind is moving fast with the advancement of technology. The current scientific community talks about the revolutionary changes achieved in the cultivation of crops, both agriculturally and organically, on many global platforms. While agricultural products provide nutritional balance, chemical products and medicines are holding back human progress. In this age where medicine has become a food and a scene of irritation and agitation, the need to distinguish between good and bad rests upon us. We are unique as individuals at every level of human development. At the genetic level, the body reacts differently to different environments in terms of the food and medicine we take.

The facts that genes dictate response to drug therapy have been known for more than half-a-century. Drug reactions are the largest cause of long-term mortality. These are ahead of road accidents and lifestyle diseases. However, many deaths can be prevented with the basic understanding that drugs work differently for each person. This leads us to a fascinating area of ​​science, pharmacogenomics. (Bansal V et al, 2005).

As the name suggests, pharmacogenomics is a branch of genetics. It determines a person‘s response to a particular drug. The main goal of pharmacogenomics is to prescribe the right drug to an individual at a given time, thereby minimizing any physical side effects. However, many hurdles have to be overcome to implement this. Ethical, social and legal issues need to be addressed. Pharmacoeconomic analysis, diagnostic approaches all need to be critically evaluated for new drug development using pharmacogenomics as a tool. It applies to how a particular drug is broken down, used, and excreted. In the analysis of many drugs, it depends on the DNA and its response to different drugs. This is the main reason for pharmacogenomics to prescribe precision and personalized medicine.

Advantages of Pharmacogenomics:

Pharmacogenomics combines the ancient sciences of organic, pharmaceutical, chemical sciences with information on proteins, genes and single ester polymorphisms. It has the advantages mentioned below.

• Safer drugs from early stages
• Accurate ways to determine appropriate doses.
• Timely and efficient prices
• Advanced drugs
• Lower health care costs 
• Ability to identify appropriate therapies using genetic targets

Medicamap: 

Before undergoing a pharmacogenomic test it is good to understand how your genes respond to drugs. The following points may be considered.

• Know the types of treatment combinations
• Explore alternatives in treatment
• Assessment of the body‘s reactions to a particular treatment 
• Knowing if there are side effects

Seen in the days gone by, the efficacy of medicine, its absorption was nothing but a myth. Also, because the sale of drugs is so high, their side effects have become a major cause of death. There is no truth in saying that most of the drugs given nowadays are not treating people but only removing their symptoms. Knowing about the types of medicines can help us learn many exciting facts. This information can reduce unwanted risk, increase the chances of successful treatment and save human life. With the proliferation of sequencing and genetic research technology, it is possible to test your genetic profile and understand your body‘s response to many drugs.

Our Medicamap is a state-of-the-art pharmacogenomic test that analyzes your drug-response profile to determine your unique profile based on genetic alignment. Medicamap is a saliva-based test. This test contains carefully selected genetic markers for various drugs including FDA recommended drug compounds with 99% data accuracy. Our personalized report not only gives your doctor an idea of ​​you, but also informs you of any medications that are not suitable for your body. With this test, the doctor is able to prescribe appropriate treatment options and drug dosage for the patient. 

Benefits of Medicamap:

• To help propose treatment based on your genes and drug response profile
• Besides increasing the efficacy of the drug, it also shortens the duration of your treatment.
• Reducing the chances of adverse reactions.
• Knowing your body‘s response to drugs. 

Simply put, pharmacogenomics is a practice. It is in order to lead towards maximum benefits and uses. Key features of this test include improvement in drug efficacy and adverse reactions, correlation between disease symptoms and genes, and identification of targets in new drug research. In retrospect, most drugs are designed to target a population rather than targeting an individual or patient. By reversing that trend, pharmacogenomics could not only improve the focus of treatment, but also provide more effective, lower doses of drugs for relief. Instead of relying on the external manifestation of the disease, pharmacogenomic medicine not only examines the genotype, but also treats it. The gradual incorporation of pharmacogenomic studies into drug discovery and development will significantly reduce costs associated with drug development. Therefore, many potential drugs rejected in a study using a pharmacogenomic study due to effects on outliers may be retained in the future.

Taken together, we can expect this personalized medicine to lead stakeholders of all kinds to more efficient decision-making on a wide range of medical care options than ever before. Making such decisions, as well as designing systems of treatment to use health care resources, requires more than ever financial support from the government. Alternatively, you can visit   our website www.mapmygenome.in .

Email :  info@mapmygenome.in .  Toll Free Number : 1800 102 4595 (1800 102 4595). 

References:

1. Bansal, V., V. Kumar, and B. Medhi. "Future challenges of pharmacogenomics in clinical practice." JK Science 7.3 (2005): 176-179.
2. TP, Aneesh et al. “Pharmacogenomics: the right drug to the right person.” Journal of clinical medicine research vol. 1,4 (2009): 191-4. doi:10.4021/jocmr2009.08.1255
3. Vogenberg, F Randy et al. “Personalized medicine: part 1: evolution and development into theranostics.” P & T: a peer-reviewed journal for formulary management vol. 35,10 (2010): 560-76.