BIN3

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Description

The BIN3 (bridging integrator 3) is a protein-coding gene located on chromosome 8.

Bridging integrator 3 is a protein encoded by the BIN3 gene in humans. It belongs to the BAR domain protein family, characterized by a coiled-coil structure that mediates dimerization, senses and induces membrane curvature, and binds small GTPases. This domain is essential for the protein's function in various cellular processes, including endocytosis, intracellular transport, and potentially other roles.

BIN3 is also known as -.

Associated Diseases

• Parkinson disease
• refractive error
• type 2 diabetes mellitus
• common variable immunodeficiency
• erythroleukemia, familial, susceptibility to
• immunodeficiency 75
• dehydrated hereditary stomatocytosis