BARX1

---

Description

The BARX1 gene, plays a crucial role in embryonic development, particularly in the formation of the heart, lungs, and digestive system. It encodes a transcription factor that controls the expression of other genes involved in these processes. BARX1 mutations can disrupt these developmental pathways, leading to a range of congenital abnormalities and diseases. Research on BARX1 has shed light on the complex interplay between genetic factors and developmental disorders, providing insights into potential therapeutic targets and strategies.

Associated Diseases

• Cardiovascular defects
• Lung hypoplasia
• Esophageal atresia
• Tracheoesophageal fistula
• Anorectal malformations
• Gastrointestinal malformations

Did you know?

BARX1 is named after its "barx" domain, a conserved DNA-binding motif that is found in other transcription factors involved in development.