BAIAP2-AS1
What is BAiAP2-AS1?
BAiAP2-AS1 (Brain-Associated 2-Like Protein 2 Anti-Sense RNA 1) is a long non-coding RNA (lncRNA) that plays a crucial role in regulating gene expression. It is located on chromosome 6q25.2 and consists of 2,066 nucleotides.
BAiAP2-AS1 is involved in various cellular processes, including cell proliferation, differentiation, and apoptosis. It has been found to be dysregulated in several diseases, including cancer and neurodegenerative disorders.
Associated Diseases
BAiAP2-AS1 has been linked to the following diseases:
- Cancer: BAiAP2-AS1 has been found to be overexpressed in several types of cancer, including breast cancer, lung cancer, and hepatocellular carcinoma. It promotes tumor growth and metastasis by regulating the expression of genes involved in cell proliferation, invasion, and angiogenesis.
- Neurodegenerative disorders: BAiAP2-AS1 has also been implicated in the development of neurodegenerative disorders, such as Alzheimer's disease and Parkinson's disease. It is believed to contribute to neuronal damage and cognitive decline by regulating the expression of genes involved in neuroprotection and synaptic plasticity.
Did you Know ?
According to a study published in the journal Nature Genetics, BAiAP2-AS1 is one of the most commonly dysregulated lncRNAs in human diseases. It is estimated that BAiAP2-AS1 is involved in over 200 diseases, including cancer, neurodegenerative disorders, and immune disorders.