BACH2
Description
The BACH2 gene encodes a transcription factor that plays a vital role in regulating the development and function of immune cells, particularly B cells and T cells. It acts as a key regulator of various immune processes, including antibody production, inflammation, and immune tolerance. BACH2‘s intricate role in the immune system makes it a potential target for therapeutic interventions in various immune-related diseases.
Associated Diseases
- Autoimmune diseases, such as systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA)
- Immunodeficiency disorders
- Cancers, including lymphoma and leukemia
Did you know?
BACH2 is involved in the regulation of the expression of the transcription factor BLIMP1, which is essential for the development of plasma cells, the antibody-producing cells of the immune system.