AWAT1

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Description

The AWAT1 (acyl-CoA wax alcohol acyltransferase 1) is a protein-coding gene located on chromosome X.

AWAT1 is an acyltransferase that catalyzes the formation of wax monoesters by combining fatty alcohols and fatty acyl-CoAs. It demonstrates a strong preference for decyl alcohol (C10) over C16 and C18 alcohols, and for saturated acyl-CoAs. This enzyme is critical for the synthesis of wax esters, which play a vital role in various biological functions.

AWAT1 is also known as DGA2, DGAT2L3.

Associated Diseases

• Brugada syndrome
• familial atrial fibrillation
• Brugada syndrome 9
• familial sick sinus syndrome
• long QT syndrome 11
• Brugada syndrome 8
• long QT syndrome 10
• Brugada syndrome 3
• long QT syndrome 14
• long QT syndrome 9
• sinoatrial node dysfunction and deafness
• sick sinus syndrome 1
• atrial fibrillation, familial, 9
• long QT syndrome 12
• Jervell and Lange-Nielsen syndrome 1
• long QT syndrome 1