ATP8B2
Description
The ATP8B2 (ATPase phospholipid transporting 8B2) is a protein-coding gene located on chromosome 1.
ATP8B2 is a crucial part of the P4-ATPase flippase complex, which uses energy from ATP hydrolysis to move phosphatidylcholine (PC) from the outer layer of the cell membrane to the inner layer. This process is essential for maintaining the balance of lipids within the cell membrane.
ATP8B2 is also known as ATPID.
Associated Diseases
- type 2 diabetes mellitus
- Parkinson disease
- lysosomal storage disease
- multiple sclerosis
- Alzheimer disease
- isolated asymptomatic elevation of creatine phosphokinase
- pentosuria
