ASB18
Description
The ASB18 (ankyrin repeat and SOCS box containing 18) is a protein-coding gene located on chromosome 2.
ASB18 likely acts as a substrate recognition component within a protein complex called SCF-like ECS. This complex is responsible for attaching ubiquitin tags to target proteins, marking them for degradation by proteasomes.
ASB18 is also known as ASB-18.
Associated Diseases
- schizophrenia
- Crigler-Najjar syndrome type 2
- maple syrup urine disease
- sarcosinemia
- transient familial neonatal hyperbilirubinemia
- methylmalonic acidemia due to transcobalamin receptor defect
- gluthathione peroxidase deficiency
- Rotor syndrome
- Dubin-Johnson syndrome
- hypercholanemia, familial, 2
- hemolytic anemia due to glutathione reductase deficiency
