ASB13
Description
The ASB13 (ankyrin repeat and SOCS box containing 13) is a protein-coding gene located on chromosome 10.
ASB13, also known as Ankyrin repeat and SOCS box protein 13, is a human protein encoded by the ASB13 gene. It belongs to a family of proteins characterized by ankyrin repeat sequences and a SOCS box domain. The SOCS box acts as a link between SOCS proteins and the elongin B/C complex, potentially leading to their degradation. Multiple variations of the ASB13 gene exist due to alternative splicing, but their full sequences remain unclear.
ASB13 is likely a component of a protein complex called ECS (Elongin-Cullin-SOCS-box protein) that functions as an E3 ubiquitin ligase. This complex attaches ubiquitin molecules to target proteins, marking them for degradation by the proteasome.
ASB13 is also known as -.
