AS3MT
Description
The AS3MT (arsenite methyltransferase) is a protein-coding gene located on chromosome 10.
Arsenite methyltransferase is an enzyme encoded by the AS3MT gene in humans. It plays a role in the detoxification of arsenic by methylating it to less toxic forms. You can find more information about this gene and its location on the UCSC Genome Browser.
AS3MT catalyzes the transfer of a methyl group from S-adenosyl-L-methionine (AdoMet) to trivalent arsenicals, producing methylated and dimethylated arsenicals. This process involves the methylation of arsenite to form methylarsonate, which is then reduced to methylarsonite. Methylarsonite is further methylated into the less toxic dimethylarsinate (cacodylate).
AS3MT is also known as CYT19.
