ARMCX5-GPRASP2
Description
The ARMCX5-GPRASP2 (ARMCX5-GPRASP2 readthrough) is a protein-coding gene located on chromosome X.
The ARMCX5-GPRASP2 fusion gene is a novel oncogene that is involved in the development of prostate cancer. It is formed by a chromosomal translocation between chromosomes 11 and 17, which leads to the fusion of the ARMCX5 and GPRASP2 genes. The fusion protein resulting from this translocation is thought to be involved in the activation of the androgen receptor, which is a key driver of prostate cancer growth. Additionally, the fusion protein may also contribute to the development of prostate cancer by promoting cell growth and survival.
The ARMCX5-GPRASP2 fusion gene is a novel oncogene that is involved in the development of prostate cancer. It is formed by a chromosomal translocation between chromosomes 11 and 17, which leads to the fusion of the ARMCX5 and GPRASP2 genes. The fusion protein resulting from this translocation is thought to be involved in the activation of the androgen receptor, which is a key driver of prostate cancer growth. Additionally, the fusion protein may also contribute to the development of prostate cancer by promoting cell growth and survival.
ARMCX5-GPRASP2 is also known as ARMCX5-GPRASP2-BHLHB9-LINC00630, GPRASP3, bHLHb9, p60TRP.
Associated Diseases
- isolated asymptomatic elevation of creatine phosphokinase
- pentosuria
- childhood disintegrative disorder
- behavioral variant of frontotemporal dementia
- osteoarthritis
- cancer
