APOBEC3F


Description

APOBEC3F is a gene that encodes a cytidine deaminase enzyme involved in the innate immune response. It plays a critical role in defending against retroviruses, including HIV, by introducing mutations into viral DNA, rendering it non-functional. APOBEC3F also contributes to DNA damage and mutagenesis in cancer cells, potentially acting as a tumor suppressor.

Associated Diseases

Did you know?

APOBEC3F activity can be hijacked by some viruses, like HIV, which evolve to evade its antiviral effects.



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