APLP1
Description
The APLP1 gene (Amyloid Precursor-Like Protein 1) encodes a protein that shares significant similarities with amyloid precursor protein (APP), the protein associated with Alzheimer‘s disease. APLP1 plays a role in neuronal growth and development, and its interaction with APP may influence the production of amyloid-beta (Aβ) peptides, a hallmark of Alzheimer‘s disease. However, the precise role of APLP1 in the pathogenesis of Alzheimer‘s is not fully understood.
Associated Diseases
Did you know?
APLP1 is expressed in the brain and other tissues, but its expression is significantly reduced in Alzheimer‘s disease patients.
