ANTXRL
Description
ANTXR1, also known as the Tumor Necrosis Factor Receptor Superfamily Member 19 (TNFRSF19), is a gene that plays a crucial role in regulating immune responses. It encodes a transmembrane protein that serves as a receptor for the TNF-like ligand 1A (TL1A), a cytokine involved in various immune processes. Upon binding to TL1A, ANTXR1 activates signaling pathways leading to the production of inflammatory cytokines and the regulation of immune cell activation and differentiation. This intricate interplay between ANTXR1 and TL1A is essential for maintaining immune homeostasis and orchestrating immune responses against pathogens and other threats.
Associated Diseases
- Inflammatory bowel disease (IBD)
- Crohn‘s disease
- Ulcerative colitis
- Rheumatoid arthritis
- Psoriasis
- Multiple sclerosis
- Cancer (particularly colorectal cancer)
- Autoimmune diseases
Did you know?
ANTXR1 has been shown to play a role in regulating the gut microbiome, suggesting a potential link between this gene and the development of inflammatory bowel disease.
