ANP32E
Description
The ANP32E gene, also known as the Acidic Nuclear Phosphoprotein 32E gene, plays a crucial role in cellular processes, particularly in the regulation of gene expression and protein synthesis. Located on chromosome 17, ANP32E encodes a protein that is found primarily in the nucleus of cells. This protein interacts with other proteins and participates in various cellular pathways, including those involved in cell growth, differentiation, and stress response. ANP32E‘s involvement in these fundamental cellular functions makes it a significant player in maintaining overall cellular homeostasis.
Associated Diseases
- Cancer: Mutations in ANP32E have been linked to increased risk of certain types of cancer, including leukemia and lymphoma.
- Neurological Disorders: Altered expression of ANP32E has been implicated in the development of neurodegenerative diseases such as Alzheimer‘s disease and Parkinson‘s disease.
- Immune System Dysfunction: ANP32E plays a role in immune regulation, and its dysregulation may contribute to autoimmune disorders.
Did you know?
The ANP32E protein has been found to interact with the p53 tumor suppressor protein, a key regulator of cell cycle and apoptosis.
