ANP32B
Description
The ANP32B gene encodes a protein called acidic leucine-rich nuclear phosphoprotein 32B. This protein is involved in various cellular processes, including ribosome biogenesis, RNA splicing, and DNA repair. It resides in the nucleus and cytoplasm, interacting with various proteins to regulate these functions. ANP32B plays a role in maintaining cellular homeostasis, and its dysfunction can lead to several diseases.
Associated Diseases
- Cancer: ANP32B overexpression has been linked to increased tumor growth and metastasis in some cancers.
- Neurological disorders: Dysregulation of ANP32B has been implicated in neurodegenerative diseases like Alzheimer‘s and Parkinson‘s.
- Immune system disorders: ANP32B is involved in immune cell development and function, and its abnormal expression might contribute to autoimmune diseases.
- Developmental disorders: Alterations in ANP32B expression have been associated with certain developmental disorders.
Did you know?
ANP32B exhibits a remarkable ability to interact with a vast array of proteins, reflecting its diverse roles in cellular processes.
