ANKRD13D

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Description

The ANKRD13D (ankyrin repeat domain 13D) is a protein-coding gene located on chromosome 11.

ANKRD13D is a ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin, but not 'Lys-48'-linked ubiquitin. It plays a role in regulating the internalization of activated EGFR by binding to ubiquitinated EGFR at the cell membrane.

ANKRD13D is also known as -.

Associated Diseases

• Alzheimer disease
• nonpapillary renal cell carcinoma
• achalasia-alacrima syndrome