ANGPTL7
Description
The ANGPTL7 (angiopoietin like 7) is a protein-coding gene located on chromosome 1.
ANGPTL7 (Angiopoietin-related protein 7) is a protein encoded by the ANGPTL7 gene in humans. It belongs to the family of 8 angiopoietin-like proteins. Rare protein-altering variants in ANGPTL7, such as p.Gln175His (0.007 minor allele frequency in Non-Finnish European population) and p.R220C (0.048 minor allele frequency in Finland), have been shown to lower intraocular pressure and protect against glaucoma.
ANGPTL7 is also known as AngX, CDT6, dJ647M16.1.
