ANAPC10
Description
The ANAPC10 (anaphase promoting complex subunit 10) is a protein-coding gene located on chromosome 4.
Anaphase-promoting complex subunit 10 is an enzyme that in humans is encoded by the ANAPC10 gene. ANAPC10 has been shown to interact with CDC27, Mothers against decapentaplegic homolog 3 and Mothers against decapentaplegic homolog 2.
ANAPC10 is a subunit of the anaphase-promoting complex/cyclosome (APC/C), a crucial enzyme that regulates the cell cycle. The APC/C acts as an E3 ubiquitin ligase, tagging target proteins for degradation. This process is essential for controlling the progression through mitosis and the G1 phase of the cell cycle. The APC/C mainly facilitates the formation of 'Lys-11'-linked polyubiquitin chains, but it can also form 'Lys-48'- and 'Lys-63'-linked chains to a lesser extent.
ANAPC10 is also known as APC10, DOC1.
