ALOX15P1
Description
The ALOX15P1 (arachidonate 15-lipoxygenase pseudogene 1) is a pseudo gene located on chromosome 17.
ALOX15P1 is a gene that encodes a protein called 15-Lipoxygenase-1. This enzyme plays a key role in the metabolism of arachidonic acid, a fatty acid that is involved in a wide range of biological processes. The protein encoded by ALOX15P1 converts arachidonic acid into 15(S)-hydroxyeicosatetraenoic acid (15-HETE), a bioactive lipid mediator that has been implicated in inflammation, cell proliferation, and angiogenesis.
ALOX15P1, also known as 15-Lipoxygenase-1, is a key enzyme involved in the metabolism of arachidonic acid. It catalyzes the oxygenation of arachidonic acid to form 15(S)-hydroxyeicosatetraenoic acid (15-HETE), a bioactive lipid mediator with diverse biological functions. 15-HETE has been implicated in various physiological processes, including inflammation, cell proliferation, and angiogenesis. ALOX15P1 plays a role in regulating the inflammatory response by producing 15-HETE, which can modulate the activity of immune cells. It is also involved in the biosynthesis of lipoxins, a group of anti-inflammatory mediators that counterbalance the effects of pro-inflammatory leukotrienes. ALOX15P1's activity is tightly regulated, and its expression and function are influenced by various factors, including hormones, cytokines, and environmental stimuli. Dysregulation of ALOX15P1 activity has been linked to a number of human diseases, including cancer, cardiovascular disease, and inflammatory disorders.
ALOX15P1 is also known as ALOX15P.
