ALDH2

Description

The ALDH2 gene encodes the mitochondrial aldehyde dehydrogenase 2 enzyme, a crucial component of the alcohol metabolism pathway. This enzyme converts acetaldehyde, a toxic byproduct of alcohol breakdown, into acetate, a less harmful compound. Variations in the ALDH2 gene can significantly impact alcohol tolerance, susceptibility to alcohol-related disorders, and overall health.

Associated Diseases

Did you know?

Individuals with a common ALDH2 gene variant (ALDH2*2) experience flushing, nausea, and rapid heartbeat after consuming even small amounts of alcohol. This is often referred to as the "Asian flush" and is thought to be a protective mechanism against excessive alcohol consumption.


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