AKAP11
Description
AKAP11, or A-kinase anchoring protein 11, is a scaffolding protein that plays a crucial role in regulating diverse cellular processes. It acts as a hub for various signaling pathways, primarily those involving protein kinase A (PKA). AKAP11 facilitates the spatial and temporal control of PKA activity by anchoring it to specific subcellular locations, ensuring targeted signaling events. This intricate interplay of protein interactions and localization contributes to the regulation of a wide range of cellular functions, including ion channel activity, cell growth, and neuronal plasticity.
Associated Diseases
Did you know?
AKAP11 is highly expressed in the heart and brain, suggesting its critical role in these organ systems.