AIM1

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Description

The AIM1 gene, also known as interferon-inducible transmembrane protein 1 (IFITM1), plays a crucial role in the innate immune system. It encodes a transmembrane protein that localizes to the cell membrane and intracellular compartments. AIM1 acts as an antiviral factor, inhibiting viral entry and replication by interfering with viral membrane fusion. Additionally, AIM1 contributes to the regulation of inflammation by modulating signaling pathways involved in immune responses. Its expression is induced by interferons, a group of cytokines crucial for antiviral defense, highlighting its significance in fighting viral infections.

Associated Diseases

• Viral infections (e.g., influenza, dengue, HIV)
• Autoimmune diseases (e.g., systemic lupus erythematosus)
• Cancer

Did you know?

AIM1 has been shown to have a protective effect against COVID-19 infection, contributing to the body's ability to fight off the virus.