AGPAT6
AGPAT6: A Gene Linked to Metabolic Disorders and Heart Health
Description
AGPAT6 is a gene that encodes an enzyme involved in the synthesis of triglycerides, a type of fat molecule that stores energy in the body. Mutations in the AGPAT6 gene can lead to various metabolic and cardiovascular diseases.
Associated Diseases
Mutations in AGPAT6 have been associated with the following conditions:
- Hypertriglyceridemia: High levels of triglycerides in the blood.
- Type 2 Diabetes: A metabolic disorder characterized by insulin resistance and elevated blood sugar levels.
- Obesity: A condition characterized by excessive body fat.
- Cardiovascular Disease: Heart disease, stroke, and peripheral artery disease.
Did you Know ?
According to the National Institutes of Health (NIH), the prevalence of AGPAT6 mutations in the general population is approximately 1 in 1,000. However, it is more common in certain ethnic groups, such as individuals of African descent.
