AGBL3
Description
The AGBL3 gene encodes a protein known as the E3 ubiquitin ligase AGBL3. This protein plays a crucial role in the ubiquitin-proteasome system (UPS), a cellular machinery responsible for degrading misfolded or damaged proteins. AGBL3 specifically targets proteins involved in various cellular processes, including signal transduction, DNA repair, and apoptosis, for degradation. This precise control of protein turnover is essential for maintaining cellular homeostasis and preventing disease.
Associated Diseases
Did you know?
AGBL3 is highly expressed in the brain and plays a role in the regulation of neuronal development and function.
