ADPRHL2
Description
ADPRHL2 (ADP-ribosylhydrolase 2) is a gene that encodes an enzyme involved in DNA repair and cell cycle regulation. This enzyme removes ADP-ribose modifications from proteins, playing a crucial role in various cellular processes, including DNA damage response, chromatin remodeling, and signal transduction. Mutations in the ADPRHL2 gene have been linked to various human diseases, highlighting its importance in maintaining cellular homeostasis.
Associated Diseases
- Cancer (including breast, colorectal, and lung cancers)
- Neurodevelopmental disorders
- Immune deficiencies
- Fanconi anemia
- Ataxia telangiectasia
Did you know?
ADPRHL2 is part of a family of enzymes called ADP-ribosylhydrolases, which are involved in a variety of cellular functions, including DNA repair, cell signaling, and immune responses.
